A major transition in the evolution of life occurred when mammals evolved from one lineage of reptiles. This transition began during the Permian (286 - 248 million years ago), when the reptile group that included Dimetrodon gave rise to the "beast-faced" therapsids. (The other major branching, the "lizard-faced" sauropsids, gave rise to birds and modern reptiles). These mammal-like reptiles in turn gave rise to the cynodonts e.g. Thrinaxodon during the Triassic period.

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